Salavati Lab

 

Institute of Parasitology

 

McGill University

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ICodPack: a package for information-based analysis of codon usage

 

 

The software package that can be downloaded below provides a means for analysis of codon usage distribution among different gene sets and biological networks, and also for prediction of protein-protein interactions and gene function based on codon usage. You are granted a royalty-free non-transferable right to use the software and accompanying documentation included in this downloadable package strictly for academic research and education purposes. If you intend to use the software for any other purpose, please contact Dr. Reza Salavati.

 

 

Windows

 

Download the ICodPack from here: ICodPack.zip (38,431 KB). This package contains:

 

MIvRSCU: An application for information-based analysis of codon usage distribution among different gene sets.

 

MIvCont: A general-purpose application for information-based analysis of distribution of any continuous-type data among different gene sets.

 

NOTE (Jan 30, 2010): We have come to realize that the algorithm used in MIvCont is very similar in concept to the algorithm of the recently published iPAGE by Goodarzi et al. The two algorithms have been however developed independently. As iPAGE provides a more rigorous statistical analysis particularly for identification of deregulated gene sets, and provides many additional features that were never meant to be implemented in MIvCont, we suggest that you use iPAGE.

 

MIvDisc: A general-purpose application for information-based analysis of distribution of any discrete-type data among different gene sets.

 

PI-RSCU: An application for analysis of the correlation between similarity of codon usage and likelihood of interaction in a biological network. PI-RSCU also creates and validates a Bayesian network that can predict interactions among genes based on their codon usages. Please also see our note about analysis of codon usage using DICE.

 

PCoBClust: An application for prediction of gene function (or any other discrete gene feature) based on codon usage.

 

ICodPack.zip also contains precompiled datasets for human and Trypanosoma brucei, located in the “data” folder.

 

 

Linux

 

Not available.

 


 

 

Reza Salavati’s profile at McGill

Last updated on 7/27/2010 2:58:48 AM