Svetlana Komarova Lab

Svetlana Komarova McGill University


Svetlana Komarova Lab

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Our People


Dr. Komarova S.V.

I have a M.Sc. degree in physics from the Moscow State University, Russia (1991), and a Ph.D. degree in biophysics from the Institute of Theoretical and Experimental Biophysics, Pushchino, Russia(1996). I have completed postdoctoral training at NASA Ames Research Center and in the CIHR Group in Skeletal Development and Remodeling, UWO and joined the Faculty of Dentistry at McGill in 2004.
List of Publications
Dr. Svetlana Komarova

Jenna Fong

I received my Honours BSc (Biology with Biotechnology option) from the University of Ottawa. I am currently in the third year of my PhD, investigating cell interactions in the bone microenvironment. This includes cells with emerging effects on bone homeostasis, like cancer cells and adipocytes.
Jenna Fong

Dr. Kerstin Tiedemann

In 1994, I received a M.Sc. degree in Cell and Molecular Biology at Lund University in Sweden, followed by a Ph.D. in Biochemistry at the same university in 2000. Between 2000 and 2004, I was a postdoctoral fellow at the University of Lubeck in Germany, studying the biology and biochemistry of fibrillin and other microfibril-associated proteins of the extracellular matrix in health and disease. Since 2005, I have been working at McGill University as a research associate. My general interests and expertise are in extracellular matrix biology, in particular, the functional consequences of cell and protein interactions. In Dr. Komarova�s lab, I focus on the identification of unknown osteoclastogenic factors that are secreted to the extracellular space from either breast cancer cells or from normal proliferating cells. Another goal is to reveal cellular signalling events triggered by these osteoclastogenic factors using osteoclast precursor cells.
List of Publications
Kerstin Tiedemann,Dr.

Dr. Osama Hussein, MD, DS

My current research interest is the molecular interactions of breast cancer cells with host cells at the sites of bone metastases. My PhD project supervised by Dr. Komarova puts the focus on osteoclasts, these wonderful cells at the cross road of the skeletal, immunological and haematological systems of the body and how they change the fate of a breast cancer lesion. Research and discovery is the most exciting aspect of my career although I have always been a dedicated breast cancer professional. I have an Honour Medical degree (1993), Master (1998) and Doctoral (2004) degrees in Surgery, all from Mansoura University in Egypt. I specialized in cancer and had clinical training in breast surgery in Mansoura, Egypt (1995-2003) with modules in Milan (2005) and Pavia (2008), Italy. I have received fellowship support from the Quebec's Merit Fellowship program for Foreign Students (2010-2009), McGill University (2008-2009), McGill University Health Center (2008-2009) and the European Cancer Organization (2008).
List of Publications
Osama Hussein,Dr.

Dr. Gulzhakhan Sadvakassova

I have received my Honors M.Sc. degree from the Kazakh State University, and my PhD degree from the Institute of Molecular Biology and Biochemistry. At that time I investigated the phenol compounds degradation by peroxidase and polyphenoloxidase. Later, I have worked on the production of ELISA-based virus testing kits, and the introduction of virus-free potato seeds technology for the Ministry of Agriculture in Kazakhstan. I have worked in the Dept. of Endocrinology, Pharmacology of the McGill University since 1998 and in 2008 I have joined the Faculty of Dentistry. The subject of my investigation was the biological activity of progranulin and the haemopoetic activity of trombospondin on the erythroid precursor cells, as well as the activation of the corresponding cell signaling pathways. In Dr. Komarova's lab I will concentrate on the effects of proliferating blood cells on bone remodeling.
List of Publications
Gulzhakhan G. Sadvakassova

Shahrzad Rafiei







Shahrzad Rafiei

Salwa Maria







Shahrzad Rafiei

Past lab members


Damien Le Nihouannen, PhD.

Postdoctoral Fellow. I received my M.Sc. in Dental and Osteoarticular Tissue, Biomaterials and Biofonctionality (University of Paris, France) and then pursued my Ph.D. degree at the Laboratory for Osteoarticular and Dental Tissue Engineering (INSERM U791, University of Nantes, France) where I studied multiphasic materials for bone tissue engineering. After this typical frenchy beginning I decided to move on the other side of the Atlantic Ocean and I started a postdoctoral fellowship at McGill University in the summer 2006. My current research interests focus on osteoclast metabolism and the effect of metabolites on osteoclast function. Additionally, I investigate the complex relationship between osteoblasts and osteoclasts. During my second life, I work on resorbable calcium phosphate materials as sustained release matrices with Dr. Jake Barralet.
List of Publications
Damien Le Nihouannen, PhD

Osama Maria







Osama Maria