Functional genome
annotation by combined analysis across microarray studies of Trypanosoma brucei Supplementary
Information Najafabadi H.S. and Salavati R. NOTE: All the files that can be directly downloaded
from this page are compressed. You will need to unzip the files, using an
application such as 7-zip,
before viewing or editing them. Part 1: Coexpression networks of Trypanosoma
brucei genes The coexpression networks CoExp1Tbr and
CoExp2Tbr can be found here
(you need Cytoscape
to open this file). This file also contains the conserved coexpression
network based on comparison of expression profiles of T. brucei genes and their orthologs in L. infantum. Part2: Finding informative regulatory elements from clusters of
coexpressed genes T. brucei genes were clustered using either Iclust or a K-means approach. To
download the gene clusters based on Iclust, click here.
To download the gene clusters based on K-means with 82 clusters, click here, and for K-means with
19 clusters click here. Two different sets of
sequences were used, complete
3′ UTR sequences based on predictions of Benz et al., and truncated 3′ UTR sequences
that were at most 1000nt long. The results of running FIRE on these datasets
are as follows:
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